Completed in 2019

This study looked into incidence of STIs in men taking HIV pre-exposure prophylaxis (PrEP).

This was a longitudinal study of 2981 mostly gay and bisexual men who were taking daily PrEP. Participants received quarterly HIV and STI testing, and clinical monitoring.

In our study group of gay and bisexual men who received daily HIV pre-exposure prophylaxis (PrEP), we found that a small group of 25% were more likely to have STIs.

The results found that there was an increase in STIs in some people after taking PrEP compared to before taking PrEP. These findings highlight the importance of frequent STI testing among gay and bisexual men using PrEP.

Publications

Association of HIV preexposure prophylaxis with incidence of sexually transmitted infections among individuals at high risk of HIV infection

Traeger MW, Cornelisse VJ, Asselin J, Price B, Roth NJ, Willcox J, Tee BK, Fairley CK, Chang CC, Armishaw J, Vujovic O, Penn M, Cundil P, Forgan-Smith G. Gall J, Pickett C, Lal L, Mak A, Spelman TD, Nguyen L, Murphy DA, Ryan KE, El-Hayek C, West M, Ruth M, Batrouney C, Lockwood JT, Hoy JF, Hellard ME, Stoové MA, Wright EJ

(2019), JAMA,

DOI: 10.1001/jama.2019.2947